Vitamin B12 absorption in megaloblastic anaemia

The absorption of vitamin B12 in megaloblastic anaemia associated with pregnancy.

The absorption of (60)CoB(12) has been studied in a group of patients suffering from megaloblastic anaemia associated with pregnancy and in a control group. The mean urinary excretion of (60)CoB(12) in the patients with megaloblastic anaemia is not significantly different from that of the control group. Five of the 30 patients showed a value towards the lower limit of normal, but the serum vita...

The absorption of vitamin B12 in the megaloblastic anaemias.

Changes in serum vitamin B12 levels in patients with megaloblastic anaemia treated with folic acid.

In 21 patients with megaloblastic anaemia associated with the tropical malabsorption syndrome serum vitamin B(12) levels have been measured serially before and during parenteral folic acid therapy. In 11 patients there was a significant rise in serum B(12) levels, reaching a peak three to 17 days after starting the folic acid. In three of these cases, absorption of labelled B(12) was the same b...

Folic Acid and Vitamin B12 Levels in Pregnancy and Their Relation to Megaloblastic Anaemia.

There is a significant fall in the serum folic acid level during pregnancy, reaching its lowest level at term. This is most pronounced in twin pregnancies. A similar but less spectacular fall occurs in the vitamin B(12) concentration. In megaloblastic anaemia both folic acid and vitamin B(12) levels are lower than in other pregnant women. The degree of megaloblastic change in the bone marrow, a...

Immunoglobulin deficiency responding to vitamin B12 in two elderly patients with megaloblastic anaemia.

Two elderly patients with vitamin B12 deficiency were found to have low immunoglobulin levels. These returned to normal on treatment with vitamin B12.